A significant proportion of children with Down’s syndrome have been shown to have reduced accommodation. The purpose of this study was to investigate any association between reduced accommodation and refractive error, strabismus, visual acuity, and other ocular parameters.
Subjects were children with Down’s syndrome enrolled in a longitudinal cohort to monitor visual development. Twenty-seven children with accurate accommodation were age-matched to children with reduced accommodation based on their most recent assessment for which a full, reliable data set was available. Each child was used only once for matching. Cross-sectional ocular and visual data were analyzed using χ2 or Fisher’s exact test, or the Mann–Whitney U test for (non-normally distributed) quantitative data.